IL18 Polyclonal Antibody
Product Sizes
60 ul
£235.00
E-AB-93262-60UL
120 ul
£346.00
E-AB-93262-120UL
200 ul
£541.00
E-AB-93262-200UL
About this Product
- SKU:
- E-AB-93262
- Additional Names:
- Interleukin;IL-1F;Ig;Il-Igif;Il-18;IFN-gamma-inducing factor;Il;IL-1 gamma;IL-1F4;IL-1g;Interferon gamma-inducing factor;Interferon-gamma-inducing factor;Interleukin-1 gamma;Interleukin-18;Igif;Il18;Igif;Il-;Il-18
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Interleukin-18 (L-18) is a cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. IL-18 works by binding to the interleukin-18 receptor, and together with IL-12 it induces cell-mediated immunity following infection with microbial products like lipopolysaccharide (LPS). After stimulation with IL-18, natural killer (NK) cells and certain T cells release another important cytokine called interferon-G Gamma (IFN-G Gamma) or type II interferon that plays an important role in activating the macrophages or other cells. The combination of this cytokine and IL12 has been shown to inhibit IL-4 dependent IgE and IgG1 production, and enhance IgG2a production in B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of mouse IL18
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-il18_polyclonal_antibody-e_ab_93262
