NOX2/gp91phox Polyclonal Antibody
Product Sizes
60 ul
£235.00
E-AB-93080-60UL
120 ul
£346.00
E-AB-93080-120UL
200 ul
£541.00
E-AB-93080-200UL
About this Product
- SKU:
- E-AB-93080
- Additional Names:
- AMCBX2,CGD,CYBB,GP91-1,GP91-PHOX,GP91PHOX,IMD34,NOX2,p91-PHOX
- Application:
- Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase, neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide of human NOX2/gp91phox
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:gp91phox_polyclonal_antibody-e_ab_93080
