MASP1 Polyclonal Antibody
Product Sizes
60 ul
£217.00
E-AB-92666-60UL
120 ul
£317.00
E-AB-92666-120UL
200 ul
£492.00
E-AB-92666-200UL
About this Product
- SKU:
- E-AB-92666
- Additional Names:
- 3MC1,CRARF,CRARF1,MAP1,MASP,MASP1,MASP3,MAp44,PRSS5,RaRF
- Application:
- Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide of human MASP1
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-masp1_polyclonal_antibody-e_ab_92666
