TTLL12 Polyclonal Antibody
Product Sizes
60 ul
£217.00
E-AB-92358-60UL
120 ul
£317.00
E-AB-92358-120UL
200 ul
£492.00
E-AB-92358-200UL
About this Product
- SKU:
- E-AB-92358
- Additional Names:
- dJ526I14.2, tubulin tyrosine ligase like 12,TTLL12
- Application:
- Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Negatively regulates post-translational modifications of tubulin, including detyrosination of the C-terminus and polyglutamylation of glutamate residues. Also, indirectly promotes histone H4 trimethylation at 'Lys-20' (H4K20me3. Probably by controlling tubulin and/or histone H4 post-translational modifications, plays a role in mitosis and in maintaining chromosome number stability. During RNA virus-mediated infection, acts as a negative regulator of the DDX58/RIG-I pathway by preventing MAVS binding to TBK1 and IKBKE.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human TTLL12
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-ttll12_polyclonal_antibody-e_ab_92358
