ZFPM1 Polyclonal Antibody
Product Sizes
60 ul
£217.00
E-AB-91990-60UL
120 ul
£317.00
E-AB-91990-120UL
200 ul
£492.00
E-AB-91990-200UL
About this Product
- SKU:
- E-AB-91990
- Additional Names:
- FOG,FOG1,ZC2HC11A,ZFPM1,ZNF408,ZNF89A
- Application:
- Immunofluorescence, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. May be involved in regulation of some genes in gonads. May also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2 (By similarity.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human ZFPM1
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-zfpm1_polyclonal_antibody-e_ab_91990
