MAP3K8 Polyclonal Antibody
Product Sizes
60 ul
£217.00
E-AB-91223-60UL
120 ul
£317.00
E-AB-91223-120UL
200 ul
£492.00
E-AB-91223-200UL
About this Product
- SKU:
- E-AB-91223
- Additional Names:
- AURA2,COT,EST,ESTF,MAP3K8,MEKK8,TPL2,Tpl-2,c-COT
- Application:
- Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation. This gene may also utilize a downstream in-frame translation start codon, and thus produce an isoform containing a shorter N-terminus. The shorter isoform has been shown to display weaker transforming activity. Alternate splicing results in multiple transcript variants that encode the same protein.
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide of human MAP3K8
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-map3k8_polyclonal_antibody-e_ab_91223
