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Antibodies

OAS1 Polyclonal Antibody

Product Sizes
60 ul
£217.00
E-AB-90909-60UL
120 ul
£317.00
E-AB-90909-120UL
200 ul
£492.00
E-AB-90909-200UL
About this Product
SKU:
E-AB-90909
Additional Names:
E18/E16,IFI-4,OAS1,OIAS,OIASI
Application:
Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
This gene is induced by interferons and encodes a protein that synthesizes 2',5'-oligoadenylates (2-5As). This protein activates latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Alternative splicing results in multiple transcript variants with different enzymatic activities. Polymorphisms in this gene have been associated with susceptibility to viral infection and diabetes mellitus, type 1. A disease-associated allele in a splice acceptor site influences the production of the p46 splice isoform. This gene is located in a cluster of related genes on chromosome 12.
Host:
Rabbit
Immunogen:
A synthetic peptide of human OAS1
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody