IL12B Polyclonal Antibody
Product Sizes
60 ul
£217.00
E-AB-90554-60UL
120 ul
£317.00
E-AB-90554-120UL
200 ul
£492.00
E-AB-90554-200UL
About this Product
- SKU:
- E-AB-90554
- Additional Names:
- IL-12/IL-23 p,IL-12 subunit p,NK cell stimulatory factor chain,NK cell Stimulating Factor Chain,CLMF p,IMD,IL12B,CLMF,CLMF2,IL-12B,IMD28,IMD29,NKSF,NKSF2,Cytotoxic lymphocyte maturation factor 40 kDa subunit,Cytotoxic Lymphocyte Maturation Factor 40 kDa subunit (CLMF p40),IL-12/IL-23 p40,NK cell Stimulating Factor Chain 2,p40,Interleukin-12 subunit beta,CLMF p40,IL-12 subunit p40,NK cell stimulatory factor chain 2,IL 12B,IL12 p40,Interleukin 12 beta chain,Interleukin 12 p40
- Application:
- Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human IL12B
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-il12b_polyclonal_antibody-e_ab_90554
