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Antibodies

Recombinant Ubiquitin K63 Monoclonal Antibody

Product Sizes
50 ul
£198.00
E-AB-81618-50UL
100 ul
£291.00
E-AB-81618-100UL
About this Product
SKU:
E-AB-81618
Additional Names:
UBB,Ubiquitin
Application:
IHC-Paraffin, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
translate.label.attr.clone:
R06-2H7
Clonality:
Monoclonal
Concentration:
300 ug/ml
Extra Details:
This gene encodes ubiquitin, one of the most conserved proteins known.Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover.Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation.Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression.This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence.Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat.Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome.
Host:
Rabbit
Immunogen:
A synthetic peptide of human Ubiquitin (linkage-specific K63)
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody