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Antibodies

Recombinant S100A4 Monoclonal Antibody

Product Sizes
50 ul
£198.00
E-AB-81606-50UL
100 ul
£291.00
E-AB-81606-100UL
About this Product
SKU:
E-AB-81606
Additional Names:
18A2;42A;CAPL;Calvasculin;FSP1;Fibroblast specific protein;Fibroblast specific protein 1;Fibroblast specific protein 1 (FSP1);Leukemia multidrug resistance associated protein;Malignan;Malignant transformation suppression 1 (MTS1);calcium Placental protein
Application:
IHC-Paraffin, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
50mm tris-glycine
translate.label.attr.clone:
R01-7H1
Clonality:
Monoclonal
Concentration:
300 ug/ml
Extra Details:
S100A4 is a member of the S100 family of calcium-binding proteins. The S100 family members have been involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A4 is known to localize to and function in the nucleus, cytoplasm of cells and the extracellular space. S100A4 has also been shown to be associated with tumor growth, motility, invasion, metastasis, angiogenesis, apoptosis and chemoresistance. It is a fibroblast-specific protein associated with mesenchymal cell morphology and motility, is expressed during epithelial-mesenchymal transformations (EMT) in vivo. It is an improved marker for lung fibroblasts that could be useful for investigating the pathogenesis of pulmonary fibrosis. Overexpression of S100A4 is correlated with a worse prognosis inpatients with various types of cancer.
Host:
Rabbit
Immunogen:
A synthetic peptide of human S100A4
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody