Recombinant PCBP2 Monoclonal Antibody
Product Sizes
50 ul
£198.00
E-AB-81594-50UL
100 ul
£291.00
E-AB-81594-100UL
About this Product
- SKU:
- E-AB-81594
- Additional Names:
- HNRNPE2;HNRPE2;PCBP2;hnRNP-E2
- Application:
- Western Blot
- Buffer:
- 50mm tris-glycine
- translate.label.attr.clone:
- R01-2F5
- Clonality:
- Monoclonal
- Concentration:
- 300 ug/ml
- Extra Details:
- The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. Thsi gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene.
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide of human PCBP2
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p-recombinant_pcbp2_monoclonal_antibody-e_ab_81594
