Recombinant LRP1 Monoclonal Antibody
Product Sizes
50 ul
£198.00
E-AB-81579-50UL
100 ul
£291.00
E-AB-81579-100UL
About this Product
- SKU:
- E-AB-81579
- Additional Names:
- A2MR;APOER;APR;CD91;IGFBP3R;KPA;LRP;LRP1;LRP1A;TGFBR5
- Application:
- IHC-Paraffin, Immunohistochemistry, Western Blot
- Buffer:
- 50mm tris-glycine
- translate.label.attr.clone:
- R09-4E8
- Clonality:
- Monoclonal
- Concentration:
- 300 ug/ml
- Extra Details:
- This gene encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer's disease patients.
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide of human LRP1
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p-recombinant_lrp1_monoclonal_antibody-e_ab_81579
