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Antibodies

Recombinant LC3A Monoclonal Antibody

Product Sizes
50 ul
£198.00
E-AB-81578-50UL
100 ul
£291.00
E-AB-81578-100UL
About this Product
SKU:
E-AB-81578
Additional Names:
ATG8E;Autophagy-related protein LC3 A;Autophagy-related ubiquitin-like modifier LC3 A;LC3;LC3A;MAP1 light chain 3 like protein 1;MAP1 light chain 3-like protein 1;MAP1A/1B light chain 3 A;MAP1A/MAP1B LC3 A;MAP1A/MAP1B light chain 3 A;MAP1ALC3;MAP1BLC3;Map
Application:
Western Blot
Buffer:
50mm tris-glycine
translate.label.attr.clone:
R05-1B6
Clonality:
Monoclonal
Concentration:
300 ug/ml
Extra Details:
LC3,also known as microtubule-associated protein 1 light chain 3 (MAP1LC3),is a mammalian homolog of the yeast Atg8p (autophagy-related 8 protein) that is involved in autophagy process. Three isoforms of LC3 exist as LC3A,LC3B,and LC3C. LC3 is first synthesized as pro-LC3,and undergoes C-terminal cleavage to yield a cytosolic precursor known as LC3-I. During autophagy LC3-I is subsequently conjugated to PE lipid as lipidated form: LC3-II. The lipidated form migrates faster on SDS-PAGE gel. The increased the level of LC3-II has been widely used as autophagy marker. This antibody recognizes both LC3-I and LC3-II.
Host:
Rabbit
Immunogen:
A synthetic peptide of human MAP1LC3A
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody