Recombinant CDC42 Monoclonal Antibody
Product Sizes
50 ul
£198.00
E-AB-81545-50UL
100 ul
£291.00
E-AB-81545-100UL
About this Product
- SKU:
- E-AB-81545
- Additional Names:
- CDC42;CDC42Hs;G25K;TKS
- Application:
- Western Blot
- Buffer:
- 50mm tris-glycine
- translate.label.attr.clone:
- R01-1C7
- Clonality:
- Monoclonal
- Concentration:
- 300 ug/ml
- Extra Details:
- The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human CDC42
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p-recombinant_cdc42_monoclonal_antibody-e_ab_81545
