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Antibodies

Recombinant APC Monoclonal Antibody

Product Sizes
50 ul
£198.00
E-AB-81529-50UL
100 ul
£291.00
E-AB-81529-100UL
About this Product
SKU:
E-AB-81529
Additional Names:
APC;Adenomatous Polyposis Coli;Adenomatous polyposis coli protein;Apc;CC1;DP2;DP2.5;DP3;Deleted in polyposis 2.5;FAP;FPC;GS;Protein APC
Application:
Western Blot
Buffer:
50mm tris-glycine
translate.label.attr.clone:
R06-2E4
Clonality:
Monoclonal
Concentration:
300 ug/ml
Extra Details:
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
Host:
Rabbit
Immunogen:
A synthetic peptide of human APC
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody