Recombinant SQSTM1/p62 Monoclonal Antibody
Product Sizes
50 ul
£198.00
E-AB-81512-50UL
100 ul
£291.00
E-AB-81512-100UL
About this Product
- SKU:
- E-AB-81512
- Additional Names:
- A170;DMRV;EBI 3 associated protein of 60 kDa;EBI 3 associated protein p60;EBI3 associated protein of 60 kDa;EBI3 associated protein p60;EBI3-associated protein of 60 kDa;EBIAP;FTDALS3;MGC127197;ORCA;OSF-6;OSIL;Osi;Oxidative stress induced like;p60;p62
- Application:
- Western Blot
- Buffer:
- 50mm tris-glycine
- translate.label.attr.clone:
- R08-4H8
- Clonality:
- Monoclonal
- Concentration:
- 300 ug/ml
- Extra Details:
- Sequestosome 1 (SQSTM1/p62) is a multifunctional adaptor protein implicated in selective autophagy,cell signaling pathways,and tumorigenesis. p62 has been implicated in shuttling ubiquitinated and sometimes aggregated proteins for autophagic degradation. As a autophagy-specific substrate,p62 is degraded during the autophagic process,which makes intracellular level of p62 as a marker for autophagy flux. p62 is at the cross-roads of several signaling pathways including Ras/ Raf/ MAPK and NFK KappaB and plays important role in cancer. p62 is a component of inclusion bodies/ protein aggregates found in human diseases,including Huntington's disease,Alzheimer's disease,Parkinson's disease in the brain,and nephropathic cystinosis in kidney (22074114,22860231,22714671). The molecular weight of p62 is predicted as 48/ 38 kDa,while western blot analyses using this antibody demonstrate the major band around 60-62 kDa in various tissues.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human SQSTM1/p62
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p62_monoclonal_antibody-e_ab_81512
