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Antibodies

Recombinant SF3B1 Monoclonal Antibody

Product Sizes
50 ul
£198.00
E-AB-81510-50UL
100 ul
£291.00
E-AB-81510-100UL
About this Product
SKU:
E-AB-81510
Additional Names:
Hsh155;MDS;PRP10;PRPF10;SAP155;SF3B1;SF3b155
Application:
IHC-Paraffin, Immunohistochemistry, Western Blot
Buffer:
50mm tris-glycine
translate.label.attr.clone:
R08-6I2
Clonality:
Monoclonal
Concentration:
300 ug/ml
Extra Details:
This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms.
Host:
Rabbit
Immunogen:
A synthetic peptide of human SF3B1
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Hamster, Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody