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Antibodies

Recombinant Semaphorin 4D Monoclonal Antibody

Product Sizes
50 ul
£198.00
E-AB-81485-50UL
100 ul
£291.00
E-AB-81485-100UL
About this Product
SKU:
E-AB-81485
Additional Names:
A8,BB 18,BB18,CD 100,CD100,CD100 antigen,COLL4,Coll 4,Collapsin 4,Collapsin4,GR3,Leukocyte activation antigen CD100,M sema G,MSEMA,SEM4D,Sema 4d,Sema H,Sema domain immunoglobulin domain Ig transmembrane domain TM and short cytoplasmic domain semaphorin 4D
Application:
Western Blot
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
translate.label.attr.clone:
R05-2E3
Clonality:
Monoclonal
Concentration:
300 ug/ml
Extra Details:
Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system, induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA.
Host:
Rabbit
Immunogen:
A synthetic peptide of human Semaphorin 4D
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody