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Antibodies

Recombinant ILF3 Monoclonal Antibody

Product Sizes
50 ul
£198.00
E-AB-81475-50UL
100 ul
£291.00
E-AB-81475-100UL
About this Product
SKU:
E-AB-81475
Additional Names:
ILF;MMP;Mpp;DRBP;NF-AT;MPHOSPH;TCP;ILF3;CBTF;DRBF;DRBP76;MMP4;MPHOSPH4;MPP4;NF-AT-90;NF110;NF110b;NF90;NF90a;NF90b;NFAR;NFAR-1;NFAR2;TCP110;TCP80;Double stranded RNA binding protein 76;Double-stranded RNA-binding protein 76;Interleukin enhancer binding factor 3;Interleukin enhancer-binding factor 3;M phase phosphoprotein 4;M-phase phosphoprotein 4;NF AT 90;Nuclear factor associated with dsRNA;Nuclear factor of activated T cells 90 kDa;Nuclear factor of activated T-cells 90 kDa;Translational control protein 80
Application:
IHC-Paraffin, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
50mm tris-glycine
translate.label.attr.clone:
R04-3C1
Clonality:
Monoclonal
Concentration:
300 ug/ml
Extra Details:
This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Host:
Rabbit
Immunogen:
A synthetic peptide of human ILF3
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody