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Antibodies

Recombinant FKBP52 Monoclonal Antibody

Product Sizes
50 ul
£198.00
E-AB-81469-50UL
100 ul
£291.00
E-AB-81469-100UL
About this Product
SKU:
E-AB-81469
Additional Names:
51 kDa FK506-binding protein;52 kDa FK506 binding protein;52 kDa FK506-binding protein;52 kDa FKBP;59 kDa immunophilin;FK506 binding protein 4;FK506-binding protein 4;FKBP 4;FKBP 52;FKBP 59;FKBP-4;FKBP-52;FKBP4;FKBP51;FKBP52 protein;FKBP59;HBI;Hsp 5
Application:
Immunofluorescence, Western Blot
Buffer:
50mm tris-glycine
translate.label.attr.clone:
R03-4A3
Clonality:
Monoclonal
Concentration:
300 ug/ml
Extra Details:
FKBP52 (FK506 binding protein 4) is a member of the immunophilin protein family that comprises intracellular protein effectors of immunosuppressive drugs,and it is known as a steroid receptor-associated protein. As a novel regulator of microtubule dynamics,FKBP52 is associated with the motor protein dynein and with the cytoskeleton during mitosis. FKBP52 is highly expressed in CNS regions susceptible to Alzheimer's,and plays a role in modulating toxicity of Abeta peptides. The protein can associate with the Tau function,and may help to decipher and modulate the events involved in Tau-induced neurodegeneration. In addition,FKBP52 is likely to play a role in growth and development of the male genitalia.
Host:
Rabbit
Immunogen:
A synthetic peptide of human FKBP52
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Hamster, Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody