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Antibodies

Recombinant Beclin 1 Monoclonal Antibody

Product Sizes
50 ul
£198.00
E-AB-81447-50UL
100 ul
£291.00
E-AB-81447-100UL
About this Product
SKU:
E-AB-81447
Additional Names:
APG6;ATG 6;ATG6;ATG6 autophagy related 6 homolog;BECN 1;BECN1;Bcl-2-interacting protein beclin;Beclin 1 (coiled coil moesin like BCL2 interacting protein);Beclin 1 autophagy related;Beclin-1;Beclin1;Becn1;C;Coiled coil myosin like BCL2 interacting protein
Application:
Western Blot
Buffer:
50mm tris-glycine
translate.label.attr.clone:
R02-8D5
Clonality:
Monoclonal
Concentration:
300 ug/ml
Extra Details:
Beclin-1 (BECN1), also known as ATG6 or VPS30, has a central role in autophagy, a process of programmed cell survival, which is increased during periods of cell stress and extinguished during the cell cycle. Beclin-1, may play a role in antiviral host defense. It protects against infection by a neurovirulent strain of Sindbis virus. Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. A progressively reduced Beclin-1 expression is reported to correlate with the primary tumor growth of squamous cell carcinoma and adenocarcinoma of the lung. Caspase-mediated cleavage of Beclin 1 promotes crosstalk between apoptosis and autophagy.
Host:
Rabbit
Immunogen:
Recombinant protein of human Beclin 1
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody