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Antibodies

Recombinant ERK2 Monoclonal Antibody

Product Sizes
50 ul
£198.00
E-AB-81446-50UL
100 ul
£291.00
E-AB-81446-100UL
About this Product
SKU:
E-AB-81446
Additional Names:
ERK;ERK 2;ERK-2;ERT1;Extracellular Signal Regulated Kinase 2;Extracellular signal-regulated kinase 2;MAP kinase 1;MAP kinase 2;MAP kinase isoform p42;MAPK 1;MAPK 2;MAPK2;MK01;Mapk1;Mitogen-activated protein kinase 1;Mitogen-activated protein kinase 2;P38
Application:
IHC-Paraffin, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
50mm tris-glycine
translate.label.attr.clone:
R07-1A9
Clonality:
Monoclonal
Concentration:
300 ug/ml
Extra Details:
This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
Host:
Rabbit
Immunogen:
A synthetic peptide of human ERK2
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody