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Antibodies

Recombinant c Myc Monoclonal Antibody

Product Sizes
50 ul
£198.00
E-AB-81443-50UL
100 ul
£291.00
E-AB-81443-100UL
About this Product
SKU:
E-AB-81443
Additional Names:
AU016757,Avian myelocytomatosis viral oncogene homolog,Class E basic helix-loop-helix protein 39,MRTL,MYC,MYCC,Myc,Myc protein,Myc proto oncogene protein,Myc proto-oncogene protein,Myc2,bHLHe39,c Myc,myc-related translation/localization regulatory factor
Application:
Western Blot
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
translate.label.attr.clone:
R05-5E2
Clonality:
Monoclonal
Concentration:
300 ug/ml
Extra Details:
This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini.
Host:
Rabbit
Immunogen:
A synthetic peptide of human c-Myc
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody