Recombinant TGF beta 1 Monoclonal Antibody
Product Sizes
50 ul
£198.00
E-AB-81441-50UL
100 ul
£291.00
E-AB-81441-100UL
About this Product
- SKU:
- E-AB-81441
- Additional Names:
- CED,LAP,TGF beta 1,TGFB
- Application:
- Western Blot
- Buffer:
- 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
- translate.label.attr.clone:
- R08-8B7
- Clonality:
- Monoclonal
- Concentration:
- 300 ug/ml
- Extra Details:
- TGFB, also named as LAP and TGFB1, is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. TGFB acts synergistically with TGFA in inducing transformation. It also acts as a negative autocrine growth factor. Dysregulation of TGFB activation and signaling may result in apoptosis. Many cells synthesize TGFB and almost all of them have specific receptors for it. TGFB positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. It is highly expressed in bone. Mutation of TGFB are the cause of Camurati-Engelmann disease (CED) which known as progressive diaphyseal dysplasia 1 (DPD1).
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of mouse TGF beta 1
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p-recombinant_tgf_beta_1_monoclonal_antibody-e_ab_81441
