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Antibodies

Recombinant EGFR Monoclonal Antibody

Product Sizes
50 ul
£198.00
E-AB-81439-50UL
100 ul
£291.00
E-AB-81439-100UL
About this Product
SKU:
E-AB-81439
Additional Names:
Cell growth inhibiting protein 40,Cell proliferation inducing protein 61,E,EGF R,EGFR,ERBB,Epidermal growth factor receptor,Epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog),erb-b2 receptor tyrosine kinase 1
Application:
Immunofluorescence, Western Blot
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
translate.label.attr.clone:
R03-6B1
Clonality:
Monoclonal
Concentration:
300 ug/ml
Extra Details:
EGFR,also named as ERBB1,is a cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. The gene resides on chromosome 7p12,encoding a 170 kDa membrane-associated glycoprotein. Recent studies have shown EGFR plays a critical role in cancer development and progression,including cell proliferation,apoptosis,angiogenesis,and metastatic spread. Mutations in this gene are associated with lung cancer.
Host:
Rabbit
Immunogen:
A synthetic peptide of human EGFR
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody