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Antibodies

Recombinant Bax Monoclonal Antibody

Product Sizes
50 ul
£198.00
E-AB-81433-50UL
100 ul
£291.00
E-AB-81433-100UL
About this Product
SKU:
E-AB-81433
Additional Names:
Apoptosis regulator BAX;BAX;BAXA;BCL2 associated X protein;BCL2 associated X protein omega;BCL2 associated X protein transcript variant delta2;BCL2L4;Bax-protein;Baxdelta2G9;Baxdelta2G9omega;Baxdelta2omega;Bcl-2-like protein 4;Bcl2-L-4;membrane isofor
Application:
IHC-Paraffin, Immunohistochemistry, Western Blot
Buffer:
50mm tris-glycine
translate.label.attr.clone:
R03-1D3
Clonality:
Monoclonal
Concentration:
300 ug/ml
Extra Details:
BAX,also named as BCL2L4,is a pro-apoptotic member of the Bcl-2 protein family,which plays a pivotal role in controlling cell life and death. Bax largely localizes to the cytoplasm of healthy cells,but accumulates on the outer mitochondrial membrane upon apoptosis induction . BAX can commit a cell to apoptosis by translocation from the cytosol to the mitochondria and permeabilization of the outer mitochondrial membrane,which leads to the release of cytochrome c from mitochondria . The expression of BAX is upregulated by the tumor suppressor protein p53,and BAX has been shown to be involved in p53-mediated apoptosis .
Host:
Rabbit
Immunogen:
A synthetic peptide of human Bax
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody