CASP3 Polyclonal Antibody
Product Sizes
60 ul
£198.00
E-AB-70388-60UL
120 ul
£291.00
E-AB-70388-120UL
200 ul
£430.00
E-AB-70388-200UL
About this Product
- SKU:
- E-AB-70388
- Additional Names:
- A830040C14Rik,Apopain,CASP-3,CASP3,CC3,CPP-32,CPP32,CPP32B,Casp3a,Caspase 3,Caspase-3 subunit p12,Cysteine p,apoptosis-related cysteine peptidase,apoptosis-related cysteine protease,apoptosis-related cysteine protease a
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 500 ug/ml
- Extra Details:
- Caspases, a family of endoproteases, are critical players in cell regulatory networks controlling inflammation and cell death. Initiator caspases (caspase-2, -8, -9, -10, -11, and -12) cleave and activate downstream effector caspases (caspase-3, -6, and -7), which in turn execute apoptosis by cleaving targeted cellular proteins. Caspase 3 (also named CPP32, SCA-1, and Apopain) proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at the beginning of apoptosis. Caspase 3 plays a key role in the activation of sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Caspase 3 can also form heterocomplex with other proteins and performs MW of 50-70 kDa. This antibody can recognize p17, p19 and p32 of Caspase 3.
- Host:
- Rabbit
- Immunogen:
- KLH conjugated Synthetic peptide corresponding to Mouse caspase3
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-casp3_polyclonal_antibody-e_ab_70388
