FAS Polyclonal Antibody
Product Sizes
60 ul
£198.00
E-AB-70336-60UL
120 ul
£291.00
E-AB-70336-120UL
200 ul
£430.00
E-AB-70336-200UL
About this Product
- SKU:
- E-AB-70336
- Additional Names:
- ALPS 1A,ALPS1A,APO 1,APO 1 cell surface antigen,APO1,APO1 cell surface antigen,APT 1,APT1,Apo 1 antigen,Apo-1 antigen,Apo1 antigen,Apoptosis antigen 1,Apoptosis mediating surface antigen FAS,Apoptosis-mediating surface antigen FAS,CD 95,CD 95 antigen,CD95
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- FAS,also named as CD95,APO-1,APT1,FAS1 and TNFRSF6,is a receptor for TNFSF6/FASLG. It is a cell surface receptor belonging to the TNF receptor superfamily,can mediates apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains,leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance,in the antigen-stimulated suicide of mature T-cells,or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). This anti-Fas monoclonal antibody can be used to induce apoptosis in cell cultures through Fas by imitating the Fas-ligand.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Mouse FasL
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-fas_polyclonal_antibody-e_ab_70336
