Laminin beta1 Polyclonal Antibody
Product Sizes
60 ul
£198.00
E-AB-70329-60UL
120 ul
£291.00
E-AB-70329-120UL
200 ul
£430.00
E-AB-70329-200UL
About this Product
- SKU:
- E-AB-70329
- Additional Names:
- CLM;Cutis laxa with marfanoid phenotype;LAM B1;LAMB 1;LAMB1;La;Laminin B1;Laminin B1 chain;Laminin beta 1 chain;Laminin beta 1 chain precursor;Laminin beta1;Laminin subunit beta 1;Laminin subunit beta-1;Laminin-1 subunit beta;Laminin-10 subunit beta
- Application:
- Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 1.2 mg/ml
- Extra Details:
- Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. This gene encodes the beta chain isoform laminin, beta 1. The beta 1 chain has 7 structurally distinct domains which it shares with other beta chain isomers. The C-terminal helical region containing domains I and II are separated by domain alpha, domains III and V contain several EGF-like repeats, and domains IV and VI have a globular conformation. Laminin, beta 1 is expressed in most tissues that produce basement membranes, and is one of the 3 chains constituting laminin 1, the first laminin isolated from Engelbreth-Holm-Swarm (EHS) tumor. A sequence in the beta 1 chain that is involved in cell attachment, chemotaxis, and binding to the laminin receptor was identified and shown to have the capacity to inhibit metastasis.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Mouse Laminin B Beta1
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-laminin_beta1_polyclonal_antibody-e_ab_70329
