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Antibodies

BAG2 Polyclonal Antibody

Product Sizes
60 ul
£198.00
E-AB-70258-60UL
120 ul
£291.00
E-AB-70258-120UL
200 ul
£430.00
E-AB-70258-200UL
About this Product
SKU:
E-AB-70258
Additional Names:
BAG 2,BAG family molecular chaperone regulator 2,BAG-2,BAG-family molecular chaperone regulator-2,BAG2,BCL 2 associated athanogene 2,BCL2 associated athanogene 2,BCL2-associated athanogene 2,Bag2,Bcl-2-associated athanogene 2,dJ417I1.2 (BAG family molecul
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.89 mg/ml
Extra Details:
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
Host:
Rabbit
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse Bag2
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody