E-Cadherin Monoclonal Antibody
Product Sizes
60 ul
£198.00
E-AB-70249-60UL
120 ul
£291.00
E-AB-70249-120UL
200 ul
£430.00
E-AB-70249-200UL
About this Product
- SKU:
- E-AB-70249
- Additional Names:
- Arc 1,CADH1,CAM 120/80,CD 324,CD324,CD324 antigen,CDHE,Cadherin 1,Cadherin1,E-Cad/CTF3,E-cadherin,ECAD,Epithelial cadherin,LCAM,Liver cell adhesion molecule,UVO,Uvomorulin,cadherin 1 type 1 E-cadherin,cdh1,epithelial calcium dependant adhesion protein
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
- translate.label.attr.clone:
- EC125D
- Clonality:
- Monoclonal
- Concentration:
- 1.6 mg/ml
- Extra Details:
- This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites.
- Host:
- Mouse
- Immunogen:
- Recombinant protein corresponding to MouseE-cadherin
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p-e_cadherin_monoclonal_antibody-e_ab_70249
