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Antibodies

BRAF Polyclonal Antibody

Product Sizes
60 ul
£198.00
E-AB-70237-60UL
120 ul
£291.00
E-AB-70237-120UL
200 ul
£430.00
E-AB-70237-200UL
About this Product
SKU:
E-AB-70237
Additional Names:
94 kDa B raf protein,B RAF1,B Raf proto oncogene,B Raf proto oncogene serine threonine protein kinase,B raf 1,B-Raf proto-oncogene serine/threonine-protein kinase (p94),BRAF,BRAF 1,BRAF1,FLJ95109,MGC126806,MGC138284,Muri,cRmil,serine/threonine kinase
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.74 mg/ml
Extra Details:
This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.
Host:
Rabbit
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse B-Ra
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody