IL10 Polyclonal Antibody
Product Sizes
60 ul
£198.00
E-AB-70235-60UL
120 ul
£291.00
E-AB-70235-120UL
200 ul
£430.00
E-AB-70235-200UL
About this Product
- SKU:
- E-AB-70235
- Additional Names:
- Interleukin;RP11-262N;CSIF;GVHDS;IL-10;IL10A;TGIF;IL10;Cytokine synthesis inhibitory factor;Interleukin-10;MGC126450;MGC126451;RP11-262N9.1
- Application:
- Immunofluorescence, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 150 ug/ml
- Extra Details:
- Interleukin (IL)-10 is an anti-inflammatory cytokine, produced by T helper (Th) cells, macrophages, monocytes, and B cells, that plays a crucial role in preventing inflammatory and autoimmune pathologies. It downregulates the expression of Th1 cytokines, MHC class II antigens, and co-stimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. IL-10 can block NF-K KappaB activity, and is involved in the regulation of the JAK-STAT signaling pathway. IL-10, along with its receptors, describes an important role in pathogenesis of various diseases, including infectious, inflammatory, autoimmune diseases. IL-10 mutations are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.
- Host:
- Rabbit
- Immunogen:
- KLH conjugated Synthetic peptide corresponding to IL-10
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-il10_polyclonal_antibody-e_ab_70235
