ERBB2 Polyclonal Antibody
Product Sizes
60 ul
£198.00
E-AB-70195-60UL
120 ul
£291.00
E-AB-70195-120UL
200 ul
£430.00
E-AB-70195-200UL
About this Product
- SKU:
- E-AB-70195
- Additional Names:
- C erb B2/neu protein,CD340,CD340 antigen,Cerb B2/neu protein,CerbB2,ERBB2,Erb b2 receptor tyrosine kinase 2,HER 2,HER 2/NEU,HER2,Herstatin,Human epi,Verb b2 erythroblastic leukemia viral oncogene homolog 2,neuro/glioblastoma derived oncogene homolog
- Application:
- Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1.3 mg/ml
- Extra Details:
- HER2,also known as ErbB2 and Neu,is a 185-kDa transmembrane glycoprotein that is a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. It has no ligand binding domain of its own and therefore cannot bind growth factors. However,it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer,stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways,such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Amplification and/or overexpression of HER2 have been reported in numerous cancers,including breast and ovarian tumors. HER2 is a therapeutic target for the treatment of breast cancer and other carcinomas.
- Host:
- Rabbit
- Immunogen:
- KLH conjugated Synthetic peptide corresponding to Mouse ErbB2
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-erbb2_polyclonal_antibody-e_ab_70195
