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Antibodies

LEP Polyclonal Antibody

Product Sizes
60 ul
£198.00
E-AB-70170-60UL
120 ul
£291.00
E-AB-70170-120UL
200 ul
£430.00
E-AB-70170-200UL
About this Product
SKU:
E-AB-70170
Additional Names:
FLJ94114,LEP,LEPD,Leptin,Leptin (murine obesity homolog),Leptin (obesity homolog,Leptin Murine Obesity Homolog,Leptin Precursor Obesity Factor,OB,Obese,Obese protein,Obesity,Obesity Murine H,Obesity factor,Obesity homolog mouse,homolog of,mouse,mouse)
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
Clonality:
Polyclonal
Concentration:
210 ug/ml
Extra Details:
This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.
Host:
Rabbit
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse Leptin
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody