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Antibodies

beta Amyloid Polyclonal Antibody

Product Sizes
60 ul
£198.00
E-AB-70168-60UL
120 ul
£291.00
E-AB-70168-120UL
200 ul
£430.00
E-AB-70168-200UL
About this Product
SKU:
E-AB-70168
Additional Names:
A4,A4 amyloid protein,AAA,ABETA,ABPP,AD1,AICD-50,AICD-57,AICD-59,AID(50),AID(57),AID(59),Alzheimer disease amyloid protein,Amyloid beta (A4) precursor protein,Amyloid beta A4 protein,Amyloid beta protein,Amyloid intracellul,Amyloid intracellular domain 50
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
Clonality:
Polyclonal
Concentration:
308 ug/ml
Extra Details:
AB Beta derives from APP via proteolytic cleavage by proteases called A Alpha-,B Beta- and G Gamma-secretase. The A Alpha-secretase cleavage precludes the formation of AB Beta,while the B Beta- and G Gamma-cleavages generate APP components with amyloidogenic features. Amyloid beta A4 precursor protein(APP),encoded by APP gene which locate on human chromosome 21q,is a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth,neuronal adhesion and axonogenesis. APP expressed in all fetal tissues and is pronounced in brain,kidney,heart and spleen,but weak in liver. Defects in APP are the cause of Alzheimer disease type 1 (AD1).
Host:
Rabbit
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse APP
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody