ATF1 Polyclonal Antibody
Product Sizes
60 ul
£198.00
E-AB-70146-60UL
120 ul
£291.00
E-AB-70146-120UL
200 ul
£430.00
E-AB-70146-200UL
About this Product
- SKU:
- E-AB-70146
- Additional Names:
- ATF 1,ATF1,ATF1 EWS fusion gene,ATF1 FUS fusion gene,Activating transcription factor 1,Cyclic AMP dependent transcription ,Cyclic AMP dependent transcription factor ATF 1,atf1,cAMP dependent transcription factor 1,cAMP-dependent transcription factor ATF-1
- Application:
- Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.59 mg/ml
- Extra Details:
- This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6.
- Host:
- Rabbit
- Immunogen:
- KLH conjugated Synthetic peptide corresponding to Mouse ATF1
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-atf1_polyclonal_antibody-e_ab_70146
