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Antibodies

NQO1 Polyclonal Antibody

Product Sizes
60 ul
£198.00
E-AB-70139-60UL
120 ul
£291.00
E-AB-70139-120UL
200 ul
£430.00
E-AB-70139-200UL
About this Product
SKU:
E-AB-70139
Additional Names:
Azoreductase,Cytochrome b 5 reductase,DHQU,DIA 4,DIA4,DT diaphorase,DT-diaphorase,DTD,Diaphorase (NADH/NADPH),Diaphorase (NADH/NADPH) (cytochrome b 5 reductase),Diaphorase 4,Dioxin inducible 1,Menadione reductase,NAD(P)H ,NAD(P)H dehydrogenase [quinone] 1
Application:
Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
Clonality:
Polyclonal
Concentration:
350 ug/ml
Extra Details:
This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Host:
Rabbit
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse NQO1
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody