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Antibodies

EZH2 Polyclonal Antibody

Product Sizes
60 ul
£198.00
E-AB-70131-60UL
120 ul
£291.00
E-AB-70131-120UL
200 ul
£430.00
E-AB-70131-200UL
About this Product
SKU:
E-AB-70131
Additional Names:
Drosophila,ENX 1,ENX-1,ENX1,EZH 2,EZH1,EZH2,EZH2b,Enhancer of zeste,Enhancer of zeste 2,Enhancer of zeste homolog 2,Enhancer of zeste homolog 2 (Drosophila),Enx 1h,Enx1h,Histone-lysi,enhancer of zeste 2 polycomb repressive complex 2 subunit,homolog 2
Application:
Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.54 mg/ml
Extra Details:
EZH2 (enhancer of zeste homologue 2,also known as KMT6) is a member of Polycomb group (PcG) family and encodes a histone methyl transferase that has an essential role in promoting histone H3 lysine 27 trimethylation (H3K27me3) and epigenetic gene silencing. EZH2 is important for cell proliferation and inhibition of cell differentiation,and is implicated in cancer progression. Overexpression of EZH2 is a marker of advanced and metastatic disease in many solid tumors,including prostate and breast cancer. This antibody detected EZH2 protein as a single band with a molecular weight (MW) of 91-100 kDa in multiple cell lines. The phosphorylation may result in the higher molecular weight (calculated MW as 80-86 kDa). (20935635,21367748)
Host:
Rabbit
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse EZH2
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody