ROCK1 Polyclonal Antibody
Product Sizes
60 ul
£198.00
E-AB-70124-60UL
120 ul
£291.00
E-AB-70124-120UL
200 ul
£430.00
E-AB-70124-200UL
About this Product
- SKU:
- E-AB-70124
- Additional Names:
- MGC131603,MGC43611,PRO0435,Renal carcinoma antigen NY REN 35,Renal carcinoma antigen NY-R,coiled-coil-containing protein kinase 1,coiled-coil-containing protein kinase I,p160 ROCK-1,p160 ROCK1,p160 Rhoassociated coiled coil-forming protein kinase,p160ROCK
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 300 ug/ml
- Extra Details:
- This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity.
- Host:
- Rabbit
- Immunogen:
- KLH conjugated Synthetic peptide corresponding to Mouse Rock1
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-rock1_polyclonal_antibody-e_ab_70124
