SMARCA4 Polyclonal Antibody
Product Sizes
60 ul
£198.00
E-AB-70117-60UL
120 ul
£291.00
E-AB-70117-120UL
200 ul
£430.00
E-AB-70117-200UL
About this Product
- SKU:
- E-AB-70117
- Additional Names:
- ATP dependent helicase SMARCA4,ATP-dependent helicase SMARCA4,BAF 190,BAF190,BAF190A,BRG1,BRG1 associated factor 190A,BRG1 protein,BRG1-associated factor 190A,BRM/SWI2 related gene 1,Brahma protein like 1,Global transcription activator homologous sequence
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 410 ug/ml
- Extra Details:
- The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene.
- Host:
- Rabbit
- Immunogen:
- KLH conjugated Synthetic peptide corresponding to Mouse BRG1
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-smarca4_polyclonal_antibody-e_ab_70117
