CTSC Polyclonal Antibody
Product Sizes
60 ul
£217.00
E-AB-68422-60UL
120 ul
£317.00
E-AB-68422-120UL
200 ul
£492.00
E-AB-68422-200UL
About this Product
- SKU:
- E-AB-68422
- Additional Names:
- CPPI,CTSC,DPP-I,DPP1,DPPI,HMS,JP,JPD,PALS,PDON1,PLS
- Application:
- Immunofluorescence
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human CTSC
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-ctsc_polyclonal_antibody-e_ab_68422
