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Antibodies

DAZL Polyclonal Antibody

Product Sizes
60 ul
£217.00
E-AB-68311-60UL
120 ul
£317.00
E-AB-68311-120UL
200 ul
£492.00
E-AB-68311-200UL
About this Product
SKU:
E-AB-68311
Additional Names:
DAZH,DAZL,DAZL1,DAZLA,SPGYLA
Application:
Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene.
Host:
Rabbit
Immunogen:
Recombinant fusion protein of human DAZL
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody