CYP17A1 Polyclonal Antibody
Product Sizes
60 ul
£217.00
E-AB-68310-60UL
120 ul
£317.00
E-AB-68310-120UL
200 ul
£492.00
E-AB-68310-200UL
About this Product
- SKU:
- E-AB-68310
- Additional Names:
- 20 lyase,CPT7,CYP17,CYP17A1,P450C17,S17AH
- Application:
- Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human CYP17A1
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-cyp17a1_polyclonal_antibody-e_ab_68310
