DDIT3 / CHOP Polyclonal Antibody
Product Sizes
60 ul
£235.00
E-AB-68246-60UL
120 ul
£346.00
E-AB-68246-120UL
200 ul
£541.00
E-AB-68246-200UL
About this Product
- SKU:
- E-AB-68246
- Additional Names:
- C/EBPzeta;CEBPZ;CHOP;CHOP-10;CHOP10;DDIT3;DDIT3 / CHOP;GADD153
- Application:
- Immunofluorescence, Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide of human DDIT3 / CHOP
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:_chop_polyclonal_antibody-e_ab_68246
