AGR2 Polyclonal Antibody
Product Sizes
60 ul
£217.00
E-AB-67817-60UL
120 ul
£317.00
E-AB-67817-120UL
200 ul
£492.00
E-AB-67817-200UL
About this Product
- SKU:
- E-AB-67817
- Additional Names:
- AG-2,AG2,AGR2,GOB-4,HAG-2,HEL-S-116,HPC8,PDIA17,XAG-2
- Application:
- Immunofluorescence
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human AGR2 (NP_006399.1).
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-agr2_polyclonal_antibody-e_ab_67817
