SCARB2 Polyclonal Antibody
Product Sizes
60 ul
£217.00
E-AB-67744-60UL
120 ul
£317.00
E-AB-67744-120UL
200 ul
£492.00
E-AB-67744-200UL
About this Product
- SKU:
- E-AB-67744
- Additional Names:
- AMRF,CD36L2,EPM4,HLGP85,LGP85,LIMP-2,LIMPII,SCARB2,SR-BII
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human SCARB2 (NP_005497.1).
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-scarb2_polyclonal_antibody-e_ab_67744
