INS Polyclonal Antibody
Product Sizes
60 ul
£235.00
E-AB-67409-60UL
120 ul
£346.00
E-AB-67409-120UL
200 ul
£541.00
E-AB-67409-200UL
About this Product
- SKU:
- E-AB-67409
- Additional Names:
- IDDM;IDDM1;IDDM2;ILPR;INS;IRDN;Insulin;MODY10;insulin
- Application:
- Immunofluorescence, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human INS (NP_000198.1).
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-ins_polyclonal_antibody-e_ab_67409
