TLR5 Polyclonal Antibody
Product Sizes
60 ul
£217.00
E-AB-67080-60UL
120 ul
£317.00
E-AB-67080-120UL
200 ul
£492.00
E-AB-67080-200UL
About this Product
- SKU:
- E-AB-67080
- Additional Names:
- MELIOS,SLE1,SLEB1,TIL3,TLR5
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human TLR5 (NP_003259.2).
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-tlr5_polyclonal_antibody-e_ab_67080
