BBC3 Polyclonal Antibody
Product Sizes
60 ul
£235.00
E-AB-67059-60UL
120 ul
£346.00
E-AB-67059-120UL
200 ul
£541.00
E-AB-67059-200UL
About this Product
- SKU:
- E-AB-67059
- Additional Names:
- BBC3,JFY-1,JFY1,PUMA
- Application:
- Immunofluorescence, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants.
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide of human BBC3 (NP_001120713.1).
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-bbc3_polyclonal_antibody-e_ab_67059
